Man gets genetically-modified pig heart in world-first transplanton January 10, 2022 at 10:55 pm

- Advertisement -
- Advertisement -
- Advertisement -
- Advertisement -

David Bennett, 57, is doing well three days after surgery, doctors in Baltimore, Maryland, say.

Surgeon Bartley P. Griffith with David Bennett in January

Image source, University of Maryland School of Medicine

A US man has become the first person in the world to get a heart transplant from a genetically-modified pig.

David Bennett is doing well three days after the experimental seven-hour procedure in Baltimore, doctors say.

The transplant was considered the last hope of saving Mr Bennett’s life, though it is not yet clear what his long-term chances of survival are.

“It was either die or do this transplant,” Mr Bennet, 57, explained, a day before the surgery.

“I know it’s a shot in the dark, but it’s my last choice.”

Doctors at the University of Maryland Medical Center were granted a special dispensation by the US medical regulator to carry out the procedure, on the basis that Mr Bennett would otherwise have died.

For the medical team who did the transplant, it marks the culmination of years of research – and could change lives around the world.

Surgeon Bartley P. Griffith said the surgery would bring the world “one step closer to solving the organ shortage crisis”, the University of Maryland School of Medicine said in a release. That crisis means that 17 people a day in the US die waiting for an organ transplant, with more than 100,000 on the waiting list, according to

The possibility of using animal organs for so-called xenotransplantation to meet the demand has long been considered, and using pig heart valves is already common.

In October 2021, surgeons in New York announced they had successfully transplanted a pig’s kidney into a person. At the time, the operation was the most advanced experiment in the field so far.

However, the recipient on that occasion was brain dead with no hope of recovery.

Mr Bennett, however, is hoping his transplant will allow him to continue with his life. He was bedridden for six week leading up to the surgery, attached to a machine which was keeping him alive after being diagnosed with terminal heart disease.

“I look forward to getting out of bed after I recover,” he said last Thursday.

Exactly what will happen next is unclear. The pig used in the transplant had been genetically modified to knock out a gene which produces a sugar which would trigger an immune response in humans, AFP news agency reports.

Mr Griffith said they were “proceeding cautiously”, carefully monitoring Mr Bennett, while his son David Bennett Jr admitted to news agency AP they were “in the unknown at this point”.

But he added: “He realizes the magnitude of what was done and he really realizes the importance of it.”

- Advertisement -




Companies reveal their plans for what work will look like when America returns to the office

When Discover Financial Services Inc. decided to evacuate its 25,000 employees world-wide because of the COVID-19 outbreak, it did so with military efficiency in...

Brook House detention centre whistleblower ‘abuse’ inquiry beginson November 23, 2021 at 5:43 pm

Brook House was the subject of an undercover investigation for the BBC's Panorama programme in 2017.A public inquiry into the mistreatment of immigration detainees...

After Desmond Tutu, a time for new South African heroeson January 1, 2022 at 7:14 am

As the last of South Africa's moral giants is laid to rest, some say now is time to break the mould.

The Ashes: Watch the best shots from Zak Crawley’s half-century against Australiaon January 9, 2022 at 12:33 am

Watch the best shots from Zak Crawley's impressive half-century on day five of the fourth Ashes Test in Sydney.

Bernard Mongan: Failings by Army over soldier’s death, report sayson July 10, 2021 at 11:04 pm

The body of L/Cpl Bernard Mongan was discovered in his barracks three weeks after he went missing.image copyrightFamily handoutAn Army investigation into the unexplained...