There were long delays after the crash involving two HGVs, a van and a Mercedes in Cheshire.
image sourceHighways England
A man has suffered life-threatening injuries in a crash involving four vehicles on the M6 in Cheshire.
Emergency services were called to the crash involving a van, two HGVs and a Mercedes at 04:15 BST on Friday.
The southbound motorway has reopened after it was closed between junction 19 at Knutsford and junction 20 at Lymm.
The Mercedes driver, a 56-year-old man from from Newcastle-under-Lyme in Staffordshire, was taken to hospital.
Officers are appealing for anyone who witnessed the crash or has dashcam footage to get in contact.
Police have also issued 76 notices of intended prosecution to drivers on the northbound carriageway who were recorded videoing or photographing the scene while driving past.
On Thursday, the northbound carriageway near Preston, Lancashire was closed for several hours due to a fatal crash.
The driver and front seat passenger of a vehicle were pronounced dead at the scene.
The BBC is not responsible for the content of external sites.